Compositional Analysis of the High Molecular Weight Ethylene Oxide Propylene Oxide Copolymer by MALDI Mass Spectrometry
نویسندگان
چکیده
The composition of narrow distribution poly ethylene oxide-propylene oxide copolymer (Mw ~ 8700 Da) was studied using matrix assisted laser desorption ionization (MALDI) mass spectrometry. The ethylene oxide-propylene oxide copolymer produced oligomers separated by 14 Da. The average resolving power over the entire spectrum was 28,000. Approximately 448 isotopically resolved peaks representing about 56 oligomers are identified. Although agreement between experimental and calculated isotopic distributions was strong, the compositional assignment was difficult. This is due to the large number of possible isobaric components. The purpose of this research is to resolve and study the composition of high mass copolymer such as ethylene oxide-propylene oxide.
منابع مشابه
Structural Characterization of Polymers by MALDI Spiral-TOF Mass Spectrometry Combined with Kendrick Mass Defect Analysis
High-resolution mass spectrometry (HRMS) continues to play an important role in the compositional characterization of larger organic molecules. In the field of polymer characterization, however, the application of HRMS has made only slow progress because of lower compatibility between matrix-assisted laser desorption/ionization (MALDI) and ultrahigh-resolution Fourier transform ion cyclotron re...
متن کاملImproving the Resolution of Kendrick Mass Defect Analysis for Polymer Ions with Fractional Base Units
The concept of a fractional base unit for the Kendrick mass defect (KMD) analysis of polymer ions is introduced for the first time. A fraction of the ethylene oxide (EO) repeat unit (namely EO/8) has been used for the KMD analysis of a poly(ethylene oxide) and found to amplify the variations of KMD between monoisotopic and 13C isotopes, producing an isotopically resolved KMD plot at full scale ...
متن کاملFrom Fast to Slow Degradation: Different Strategies to Characterise Polymer Degradation by Chromatographic Techniques
This thesis presents different analytical strategies for the study of the degradation of synthetic polymers. Particular attention was given to the mechanisms involved at the beginning of the polymer breakdown. Three model polymers were used in order to assess different degradation rates. The first polymer studied was a stabilised polyether: Poly(ethylene oxide-propylene oxideethylene oxide) tri...
متن کاملUltrafast infrared heating laser pulse-induced micellization kinetics of poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) in water.
The heating-induced micellization of poly(ethylene oxide)-b-poly(propylene oxide)-b-poly(ethylene oxide) (Pluronic PE10300) triblock copolymer chains was studied by ultrasensitive differential scanning calorimetry, laser light scattering, and fluorescence spectrometry with a fluorescent probe, 8-anilino-1-naphthalenesulfonic acid ammonium salt. The critical micellization temperatures obtained f...
متن کاملAdsorption of a PEO-PPO-PEO triblock copolymer on metal oxide surfaces with a view to reducing protein adsorption and further biofouling.
Abstract Biomolecule adsorption is the first stage of biofouling. The aim of this work was to reduce the adsorption of proteins on stainless steel (SS) and titanium surfaces by modifying them with a poly(ethylene oxide) (PEO)-poly(propylene oxide) (PPO)-PEO triblock copolymer. Anchoring of the central PPO block of the copolymer is known to be favoured by hydrophobic interaction with the substra...
متن کامل